… to a rewarding dose of cocaine (10 mg/kg) elevating the … induced cocaine seeking in rats
after extended withdrawal from … If this holds true, our findings are in agreement with a previous …

… DA signalling prior to drug exposure affects either reward-… The most commonly used models
are the conditioned place preference (… , is targeting dopaminergic neurons and increases …

… of drug reward, such as conditioned place preference (CPP), has … showed an earlier onset
of cocaine-induced increases of … size that surpassed the threshold for being considered large. …

… Animals underwent consecutive daily rGT and cocaine self-… In Experiment 2, locomotor
testing was first performed before … , but levers would remain extended and responses monitored. …

… the pre-test was the one that was paired with cocaine during the … , the relationship between
reward thresholds and cocaine self-… differences in cocaine-induced increases in locomotor …

… Cocaine-conditioned place preference behavior and ex vivo … reward-seeking driven by
conditioned contextual associations. … priming injection before reinstatement testing (Coc-Coc), a …

… Cocaine conditioned place preference (CPP) experiments … the ratio of effort to reward to
measure cocaine-seeking, we … The observed increases in pre-synaptic sensitivity to cocaine …

… of the rewarding effects of cocaine in the conditioned place … during the pre and post
conditioning test. After each series of … Our results extend this regulation to other IEGs only in the …

… following day, they were injected with saline, given access to … 20-min access to water in the
test cages before being placed … and future assessments must extend the present analysis to …

… 30 infusions or for a 3 h time limit. For the final 6 d, the dosage of … (black) and cocaine-exposed
(gray) rats for each day of self-… Directly testing this issue has proven difficult in the past as …